Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083624 | 0.92 | TSHR (0.75) | TSHRALDH1A1THRBLMNAHSD17B10 | |
| SCHEMBL14893 | 0.90 | TSHR (0.84) | TSHRALDH1A1THRBLMNATDP1 | |
| SCHEMBL19066401 | 0.90 | TSHR (0.84) | TSHRALDH1A1THRBLMNATDP1 | |
| SCHEMBL11583525 | 0.90 | TSHR (0.84) | TSHRALDH1A1THRBLMNATDP1 | |
| Methyl Alcohol SCHEMBL3868398 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 | |
| SCHEMBL7090691 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 | |
| Ethylene SCHEMBL678650 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 | |
| SCHEMBL31757151 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 | |
| Hydrochloric Acid SCHEMBL15845918 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 | |
| SCHEMBL4019138 | 0.88 | TSHR (0.81) | TSHRALDH1A1THRBLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864544-B | A kind of high free-running property composite explosives for detonator and preparation method thereof | 南京理工大学 | 2016-07-06 | — | — | CN | disclosed |