Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055549 | 1.00 | KMT2A (0.41) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27820569 | 1.00 | KMT2A (0.41) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27839967 | 0.92 | KMT2A (0.44) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27893654 | 0.92 | KMT2A (0.44) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27970294 | 0.91 | KMT2A (0.43) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27893635 | 0.89 | KMT2A (0.41) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27910784 | 0.87 | SSTR4 (0.41) | KMT2AL3MBTL1SSTR4SSTR1KDM1A | |
| SCHEMBL28826485 | 0.85 | PRKCE (0.40) | KMT2AL3MBTL1SSTR4SSTR1SYK | |
| SCHEMBL27893646 | 0.84 | SSTR4 (0.38) | KMT2AL3MBTL1SSTR4SSTR1KDM1A | |
| SCHEMBL27910872 | 0.82 | SSTR4 (0.39) | KMT2AL3MBTL1SSTR4SSTR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470919-B | 2-(azaindole-2-base) benzimidazole as PAD4 inhibitor | 葛兰素集团有限公司 | 2016-07-06 | — | — | CN | disclosed |