SCHEMBL28055982

SCHEMBL28055982

C=C(C)C(=O)Nc1cccc(-c2ccc(C(N)=O)c3[nH]ccc23)c1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BTK Q06187 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16337822 0.91 BTK (1.00) BTK
SCHEMBL16336338 0.88 BTK (0.74) BTK
SCHEMBL16337081 0.87 BTK (0.73) BTK
SCHEMBL16336597 0.86 BTK (0.72) BTK
SCHEMBL20544071 0.85 BTK (0.70) BTK
SCHEMBL16337539 0.84 BTK (1.00) BTK
SCHEMBL16335797 0.84 BTK (0.75) BTK
SCHEMBL16335793 0.84 BTK (0.75) BTK
SCHEMBL16335794 0.84 BTK (0.75) BTK
SCHEMBL16337181 0.84 BTK (0.69) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105530932-A Primary carboxamides as BIK inhibitors ABBVIE INC 2016-04-27 CN disclosed