Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657075 | 0.86 | KMT2A (0.83) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL11884568 | 0.85 | NPC1 (0.68) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL6257291 | 0.84 | NPC1 (1.00) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| Hydrochloric Acid SCHEMBL5505787 | 0.84 | NPC1 (0.66) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL2773540 | 0.83 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL2360527 | 0.83 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL30101947 | 0.83 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL28751724 | 0.83 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL3506441 | 0.83 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL31078859 | 0.82 | KMT2A (1.00) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001133-A1 | PRMT5 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2023-01-26 | — | — | WO | disclosed |
| CN-111518026-A | Fluorescent molecular probe for identifying and detecting oxalic acid and preparation method and application thereof | 齐齐哈尔大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-105733559-B | The preparation method and application of oxamido- quinoline fluorescent molecular probe | 齐齐哈尔大学 | 2018-05-04 | — | — | CN | disclosed |
| CN-104961725-B | 4-alpha, beta-unsaturated carboxamidoquinoline compounds and preparation and application | 浙江大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-104961725-B | 4-alpha, beta-unsaturated carboxamidoquinoline compounds and preparation and application | 浙江大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106336378-A | Preparation method of quinoline-2-formic ether series | 江西师范大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-105733559-A | Oxalyl aminoquinoline derivative fluorescent molecular probe and preparation method and application thereof | 齐齐哈尔大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104961725-A | 4-alpha, beta-unsaturated carboxamidoquinoline compounds and preparation and application | UNIV ZHEJIANG | 2015-10-07 | — | — | CN | disclosed |
| CN-104961725-A | 4-alpha, beta-unsaturated carboxamidoquinoline compounds and preparation and application | UNIV ZHEJIANG | 2015-10-07 | — | — | CN | disclosed |