Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 11/20 | 0.74 |
| ▸ | PPIG | Q13427 | 6/20 | 0.69 |
| ▸ | PPIB | P23284 | 6/20 | 0.69 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056216 | 0.97 | PPID (0.70) | PPIDPPIGPPIBPREPMEN1 | |
| SCHEMBL2040043 | 0.86 | PPID (0.78) | PPIDPPIGPPIBOPRM1OPRK1 | |
| SCHEMBL2040168 | 0.85 | PPID (0.79) | PPIDPPIGPPIBHRH3 | |
| SCHEMBL31738100 | 0.84 | PPID (0.73) | PPIDPPIGPPIBMEN1KMT2A | |
| SCHEMBL2039970 | 0.84 | PPID (0.74) | PPIDPPIGPPIBHRH3 | |
| SCHEMBL28826538 | 0.81 | PPID (0.74) | PPIDPPIGPPIB | |
| SCHEMBL2039766 | 0.81 | PPID (1.00) | PPIDPPIGPPIB | |
| SCHEMBL2039651 | 0.81 | PPID (0.73) | PPIDPPIGPPIBHRH3 | |
| SCHEMBL12643852 | 0.80 | PPID (0.78) | PPIDPPIGPPIBPREP | |
| SCHEMBL2035376 | 0.79 | PPID (0.94) | PPIDPPIGPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102811998-B | Novel cyclophilin inhibitors and uses thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-03-30 | — | — | CN | disclosed |