Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ricinoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.74 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.74 |
| ▸ | FABP3 | P05413 | 9/20 | 0.69 |
| ▸ | FAAH | O00519 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ricinoleic Acid SCHEMBL1091770 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL957282 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL11598648 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL78693 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL28349268 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL11598640 | 1.00 | FFAR1 (0.74) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL28219680 | 0.99 | FFAR1 (0.72) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL8809771 | 0.99 | FFAR1 (0.72) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL18489805 | 0.99 | FFAR1 (0.72) | FFAR1FFAR4FABP3FAAHNFKB1 | |
| Ricinoleic Acid SCHEMBL18496848 | 0.99 | FFAR1 (0.72) | FFAR1FFAR4FABP3FAAHNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555850-A | Polyester polyol and polyol blends and rigid polyurethane foam manufacturing | DOW GLOBAL TECHNOLOGIES INC | 2016-05-04 | — | — | CN | disclosed |