Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200365 | 0.83 | ERN1 (0.51) | ERN1GRM5KDM4EGPR3TP53 | |
| SCHEMBL19692977 | 0.83 | ERN1 (0.51) | ERN1GRM5KDM4EGPR3TP53 | |
| SCHEMBL15307431 | 0.80 | GRM5 (0.58) | ERN1GRM5KDM4EGAAPKM | |
| SCHEMBL1346789 | 0.79 | GRM5 (0.63) | GRM5KDM4EGAATP53MAPT | |
| SCHEMBL528975 | 0.78 | SLC22A12 (0.47) | GAASMN1; SMN2 | |
| SCHEMBL28782754 | 0.77 | GRM5 (0.53) | GRM5L3MBTL1MAPTSMN1; SMN2NR1H2 | |
| SCHEMBL29712688 | 0.77 | GRM5 (0.53) | GRM5L3MBTL1MAPTSMN1; SMN2NR1H2 | |
| SCHEMBL15355043 | 0.76 | ERN1 (0.46) | ERN1GRM5KDM4EGPR3GAA | |
| SCHEMBL11064349 | 0.76 | ERN1 (0.44) | ERN1GRM5KDM4EGPR3GAA | |
| SCHEMBL9796489 | 0.76 | ERN1 (0.44) | ERN1GRM5KDM4EGPR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153063-B | Quinoline derivatives and melk inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |