Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.70 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601717 | 0.84 | HTR2C (0.70) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL190521 | 0.83 | HTR2C (0.68) | HTR2CKITPIK3R1PIK3CAKDM4E | |
| SCHEMBL1601613 | 0.83 | HTR2C (1.00) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL12789863 | 0.80 | HTR2C (0.65) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL13034670 | 0.80 | HTR2C (0.65) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL4193100 | 0.80 | HTR2C (0.65) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL31337089 | 0.80 | HTR2C (0.65) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL14083387 | 0.79 | HTR2C (0.63) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL14107782 | 0.79 | HTR2C (0.63) | HTR2CKITADRB2ADRB1ADRB3 | |
| SCHEMBL12988760 | 0.77 | HTR2C (0.60) | HTR2CKITADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105339371-A | Thieno[3,2-d]pyrimidine-6-carboxamides and analogues as sirtuin modulators | GLAXOSMITHKLINE LLC | 2016-02-17 | — | — | CN | disclosed |