Sugi Predict

Sugi Predict / Compounds / Pyridine

Pyridine

Pyridine

SCHEMBL28057558

NN1CCCC1.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.47
▸ TSHR P16473 1/20 0.47
▸ NAPRT Q6XQN6 1/20 0.47
▸ CHKA P35790 1/20 0.36
▸ CHRNB2 P17787 1/20 0.32
▸ CHRNA4 P43681 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27350264 0.78 PLD1 (0.42) TDP1TSHRNAPRTCHRNB2CHRNA4
Pyridine SCHEMBL28177478 0.78 TSHR (0.41) TDP1TSHRNAPRT
Pyridine SCHEMBL25338956 0.76 TSHR (0.50) TDP1TSHRNAPRTCHKACHRNB2
N-Methyl Pyrrolidine (Nmp) SCHEMBL15264514 0.74 TDP1 (0.47) TDP1TSHRNAPRTCHKACHRNB2
Pyridine SCHEMBL28167952 0.74 TDP1 (0.47) TDP1TSHRNAPRTCHKACHRNB2
Pyridine SCHEMBL6952793 0.73 TSHR (0.75) TDP1TSHRNAPRT
Cyclooctane SCHEMBL9180329 0.73 TSHR (0.75) TDP1TSHRNAPRT
Pyridine SCHEMBL6114733 0.73 TSHR (0.75) TDP1TSHRNAPRT
Cyclohexane SCHEMBL1898523 0.73 TSHR (0.75) TDP1TSHRNAPRT
Pyridine SCHEMBL4938377 0.73 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103124736-B Functionalized fluoroalkyl fluorophosphate salts MERCK PATENT GMBH (DE) 2016-05-11 — — CN disclosed