Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 8/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11181852 | 0.85 | LATS1 (0.37) | MAPTLMNAAGTR1CYP19A1LATS1 | |
| SCHEMBL11193866 | 0.84 | HDAC1 (0.39) | MAPTLMNAAGTR1CYP19A1LATS1 | |
| SCHEMBL980050 | 0.81 | MAPT (0.62) | MAPTLMNACYP19A1LATS1LATS2 | |
| SCHEMBL15912100 | 0.80 | MAPT (0.61) | MAPTLMNAAGTR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30866250 | 0.78 | MAPT (0.59) | MAPTLMNACYP19A1LATS1LATS2 | |
| SCHEMBL11957581 | 0.76 | MAPT (0.65) | MAPTLMNACYP19A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18538202 | 0.76 | MAPT (0.65) | MAPTLMNACYP19A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11615493 | 0.76 | MAPT (0.61) | MAPTLMNAAGTR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11194229 | 0.75 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL8490725 | 0.75 | ADORA2A (0.56) | MAPTLMNACYP19A1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473570-A | Diaminoheteroaryl substituted pyrazoles | Bayer Pharma AG | 2016-04-06 | — | — | CN | claimed |
| CN-105473570-A | Diaminoheteroaryl substituted pyrazoles | Bayer Pharma AG | 2016-04-06 | — | — | CN | disclosed |