SCHEMBL28059228

SCHEMBL28059228

O=C(O)c1c(C(=O)O)c2c(F)cc(C(=O)O)c3c(C(=O)O)cc4cccc1c4c32

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40
CDC25B P30305 2/20 0.40
GRIN2D O15399 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
GPR35 Q9HC97 2/20 0.38
AURKA O14965 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393911 0.82 KMT2A (0.45) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL10813708 0.82 KMT2A (0.45) MEN1KMT2AHSD17B10KDM4EALDH1A1
Potassium SCHEMBL30715277 0.81 KMT2A (0.44) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL28404618 0.81 KMT2A (0.44) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL28694846 0.81 KMT2A (0.44) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL345964 0.75 MEN1 (0.50) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL30020926 0.75 KMT2A (0.50) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL275150 0.75 KMT2A (0.50) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL10478169 0.73 KMT2A (0.60) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL28434936 0.72 KMT2A (0.41) MEN1KMT2AHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105474422-B Organic illuminating element 乐金显示有限公司 2018-02-09 CN claimed
CN-105474422-A Organic light emitting element LG CHEMICAL LTD 2016-04-06 CN claimed
CN-104350626-A Organic light emitting diode LG CHEMICAL LTD 2015-02-11 CN claimed
CN-105474422-B Organic illuminating element 乐金显示有限公司 2018-02-09 CN disclosed
CN-104350626-B Organic light emitting diode 乐金显示有限公司 2017-05-03 CN disclosed
CN-105474422-A Organic light emitting element LG CHEMICAL LTD 2016-04-06 CN disclosed
CN-104350626-A Organic light emitting diode LG CHEMICAL LTD 2015-02-11 CN disclosed