Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843517 | 0.82 | TSHR (0.67) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL28077328 | 0.77 | CNR2 (0.48) | TSHRUSP2ALDH1A1KDM4EMEN1 | |
| SCHEMBL1838504 | 0.75 | TSHR (0.61) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL4401988 | 0.74 | TSHR (0.70) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL1837669 | 0.74 | TSHR (0.54) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL15485172 | 0.73 | TSHR (1.00) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL282162 | 0.73 | TSHR (1.00) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL20721726 | 0.73 | TSHR (1.00) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL1838131 | 0.73 | TSHR (0.53) | TSHRHDAC4HDAC2HDAC8RORC | |
| SCHEMBL2784586 | 0.72 | TSHR (0.73) | TSHRHDAC4HDAC2HDAC8RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105439-B | Method for producing N-substituted carbamate and method for producing isocyanate using the N-substituted carbamate | ASAHI KASEI CHEMICALS CORP. (JP) | 2016-04-20 | — | — | CN | disclosed |