Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537123 | 0.86 | GLRA1 (0.40) | GLRA1SLC6A4HTR1ASLC6A2SLC6A3 | |
| SCHEMBL28739338 | 0.85 | GLRA1 (0.47) | GLRA1TDP1L3MBTL1MAOBALDH1A1 | |
| SCHEMBL17549514 | 0.84 | GLRA1 (0.39) | GLRA1SLC6A4HTR2AHTR2CTSHR | |
| SCHEMBL28739333 | 0.83 | PTGER4 (0.46) | GLRA1LMNAHPGD | |
| SCHEMBL17598364 | 0.83 | TSHR (0.41) | HTR1ASLC6A2HTR2CTSHRALOX15 | |
| SCHEMBL21154973 | 0.83 | GLRA1 (0.38) | GLRA1SLC6A4HTR2AHTR2CTSHR | |
| SCHEMBL29473847 | 0.83 | GLRA1 (0.44) | GLRA1MAPTTDP1L3MBTL1MAOB | |
| SCHEMBL28739380 | 0.82 | GLRA1 (0.44) | GLRA1MAPK1TDP1TSHRALOX15 | |
| SCHEMBL29473832 | 0.82 | GLRA1 (0.44) | GLRA1MAPK1TDP1TSHRALOX15 | |
| SCHEMBL28739300 | 0.82 | GLRA1 (0.44) | GLRA1MAPK1L3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384608-A | Isopropyl-phenol derivative and preparation method therefor | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |