SCHEMBL28060231

SCHEMBL28060231

CCCCCCCCCCCCCCCCOP(=O)(ON)OCCCCCCCCCCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.60
LPAR3 Q9UBY5 7/20 0.57
LPAR2 Q9HBW0 6/20 0.57
LPAR1 Q92633 3/20 0.57
TSHR P16473 1/20 0.47
LMNA P02545 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CDC25A P30304 1/20 0.46
AGTR1 P30556 1/20 0.46
AKT1 P31749 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46
CA1 P00915 8/20 0.42
CA2 P00918 8/20 0.42
CA9 Q16790 7/20 0.42
CA12 O43570 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA3 P07451 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27830348 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL9246534 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL6654270 0.96 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL28041080 0.94 CYP3A4 (0.54) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL28131260 0.94 CYP3A4 (0.54) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL28823676 0.94 CYP3A4 (0.54) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL2539144 0.93 CYP3A4 (0.62) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL5519381 0.91 CYP3A4 (0.73) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL258318 0.86 CYP3A4 (0.80) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL22230793 0.86 CYP3A4 (0.80) CYP3A4LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105394046-B Composition for inhibiting insect host to feel 范德比尔特大学 2019-03-01 CN disclosed
CN-105394046-A Compositions For Inhibition Of Insect Host Sensing UNIV VANDERBILT 2016-03-16 CN disclosed