Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197638 | 0.90 | — | — | |
| SCHEMBL28044800 | 0.87 | — | — | |
| Water SCHEMBL28044737 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL6069542 | 0.87 | — | — | |
| SCHEMBL30129770 | 0.87 | — | — | |
| SCHEMBL28151623 | 0.85 | HCAR2 (0.50) | HCAR2CHRNB2CHRNA4TSHRCHRNB4 | |
| Water SCHEMBL28044696 | 0.84 | HCAR2 (0.48) | HCAR2CHRNB2CHRNA4TSHRCHRNB4 | |
| SCHEMBL29111879 | 0.82 | HCAR2 (0.60) | HCAR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Formaldehyde SCHEMBL28841438 | 0.82 | HCAR2 (0.43) | HCAR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Formaldehyde SCHEMBL28184486 | 0.82 | HCAR2 (0.43) | HCAR2CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063283-A | 3-amino indazole compound and application thereof | 暨南大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-108699065-A | Tricyclic compounds and composition as kinase inhibitor | 诺华股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-106317023-A | Preparation method and application of indazole compound | 中国科学院上海药物研究所 | 2017-01-11 | — | — | CN | disclosed |
| CN-105585558-A | Double-alkoxy pyrimidine jointing 3-ethylenic-bond-oxoindole derivative and preparing method and application thereof | UNIV GUIZHOU | 2016-05-18 | — | — | CN | disclosed |