Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793206 | 0.90 | GCGR (0.65) | GCGRMAPK14 | |
| SCHEMBL28154907 | 0.80 | GCGR (0.61) | GCGRMAPK14 | |
| SCHEMBL28912040 | 0.80 | GCGR (0.82) | GCGRMAPK14 | |
| SCHEMBL28552564 | 0.80 | GCGR (0.61) | GCGRMAPK14 | |
| Piperazine SCHEMBL28145784 | 0.80 | BACE1 (0.42) | GCGRMAPK14 | |
| SCHEMBL28542916 | 0.80 | GCGR (0.61) | GCGRMAPK14 | |
| SCHEMBL4778800 | 0.76 | GCGR (0.51) | GCGRMAPK14 | |
| SCHEMBL28260523 | 0.76 | GCGR (0.64) | GCGRMAPK14 | |
| SCHEMBL28553754 | 0.76 | GCGR (0.64) | GCGRMAPK14 | |
| SCHEMBL28261804 | 0.75 | GCGR (0.54) | GCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266398-A | Phenanthro- [9,10 b] furans for electronic application | UDC 爱尔兰有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-106977550-A | Organometallic complex, light-emitting component, light-emitting device, electronic equipment and lighting device | 株式会社半导体能源研究所 | 2017-07-25 | — | — | CN | disclosed |
| CN-105981191-A | Light-emitting element, light-emitting device, electronic device, and lighting device | 株式会社半导体能源研究所 | 2016-09-28 | — | — | CN | disclosed |
| CN-103477463-B | Organic illuminating element, organometallic complex, light-emitting device, electronic equipment and illuminator | 株式会社半导体能源研究所 | 2016-08-10 | — | — | CN | disclosed |