Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943297 | 0.88 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11325297 | 0.84 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11126916 | 0.84 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL71009 | 0.81 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30514820 | 0.81 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1817387 | 0.79 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4041107 | 0.78 | MAPT (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL31345525 | 0.78 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4644640 | 0.78 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Iodomethane SCHEMBL9116697 | 0.77 | CA1 (0.52) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370318-B | The Imidazopyridazine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |