SCHEMBL28061655

SCHEMBL28061655

COC(=O)C(C(C(=O)OC)C(C)(C)C)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
CA14 Q9ULX7 4/20 0.39
CA12 O43570 3/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 1/20 0.34
TSHR P16473 2/20 0.33
DGAT1 O75907 1/20 0.33
PIK3CD O00329 1/20 0.33
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14668832 0.90 SMN1; SMN2 (0.39) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL14355029 0.89 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL5511092 0.89 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL12445335 0.89 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL22667816 0.88 SMN1; SMN2 (0.38) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL15034670 0.79 CA1 (0.42) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL15034669 0.79 CA1 (0.42) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL15034668 0.79 CA1 (0.42) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL2059192 0.79 SLC7A5 (0.44) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL12552602 0.78 SMN1; SMN2 (0.31) SMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636967-B catalyst system for olefin polymerization 沙特基础工业公司 2018-09-28 CN disclosed
CN-105636967-A Catalyst system for olefin polymerization SAUDI BASIC IND CORP 2016-06-01 CN disclosed