Hydroxyamine

Hydroxyamine

SCHEMBL28061871

NO.O=C(c1ccccc1)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.77
POLB P06746 2/20 0.77
SRD5A2 P31213 2/20 0.72
CES1 P23141 2/20 0.72
CES2 O00748 1/20 0.72
LMNA P02545 2/20 0.70
GAA P10253 1/20 0.70
ALOX5 P09917 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
TDP1 Q9NUW8 2/20 0.62
TSHR P16473 1/20 0.60
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA12 O43570 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 3/20 0.57
MAPT P10636 1/20 0.57
MEN1 O00255 1/20 0.57
NPC1 O15118 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27600926 0.96 MAPK1 (0.77) MAPK1POLBSRD5A2CES1CES2
Benzophenone SCHEMBL28231509 0.96 POLB (0.82) MAPK1POLBSRD5A2CES1CES2
SCHEMBL229627 0.96 POLB (0.82) MAPK1POLBSRD5A2CES1CES2
Hydrazine SCHEMBL27456064 0.94 MAPK1 (0.74) MAPK1POLBSRD5A2CES1CES2
Carbamic Acid SCHEMBL27688398 0.94 MAPK1 (0.74) MAPK1POLBSRD5A2CES1CES2
Methane SCHEMBL27439754 0.94 POLB (0.79) MAPK1POLBSRD5A2CES1CES2
Methane SCHEMBL29286698 0.94 POLB (0.79) MAPK1POLBSRD5A2CES1CES2
Water SCHEMBL28104393 0.94 POLB (0.79) MAPK1POLBSRD5A2CES1CES2
Hydrochloric Acid SCHEMBL28168308 0.94 POLB (0.79) MAPK1POLBSRD5A2CES1CES2
Ammonia Solution, Strong SCHEMBL27306146 0.94 POLB (0.79) MAPK1POLBSRD5A2CES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103342633-B For the preparation of the method for benzofuran compounds CAMBREX KARLSKOGA AB (SE) 2016-05-04 CN disclosed