Biphenyl

Biphenyl

SCHEMBL28062042

CN1CCCC1=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.68
BRD2 P25440 1/20 0.68
TNKS O95271 1/20 0.49
PARP1 P09874 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49
ACHE P22303 1/20 0.45
SRD5A1 P18405 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 1/20 0.41
PARL Q9H300 2/20 0.41
BRDT Q58F21 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tannin Pyrogallol SCHEMBL29240161 0.92 BRD4 (0.57) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL28570679 0.89 BRD4 (0.85) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL4003174 0.86 BRD4 (0.65) BRD4BRD2TNKSPARP1TNKS2
SCHEMBL28923209 0.85 BRD4 (0.53) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL28166861 0.85 BRD4 (0.63) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL10333525 0.85 BRD4 (0.63) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL7058561 0.85 BRD4 (0.63) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL28624214 0.85 BRD4 (0.63) BRD4BRD2TNKSPARP1TNKS2
O-Xylene SCHEMBL2472792 0.84 BRD4 (0.68) BRD4BRD2TNKSPARP1TNKS2
Methylpyrrolidone SCHEMBL27867809 0.83 BRD4 (0.61) BRD4BRD2TNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105431439-A Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUND 2016-03-23 CN disclosed