Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623824 | 0.88 | KDM4E (0.60) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL11621817 | 0.86 | KDM4E (0.57) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL11623041 | 0.85 | KDM4E (0.56) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL28309288 | 0.84 | SMN1; SMN2 (0.49) | KDM4EGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28875274 | 0.84 | EGLN1 (0.44) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL11623795 | 0.83 | GAA (0.60) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL11624794 | 0.83 | KDM4E (0.57) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL17266779 | 0.82 | EGLN1 (0.43) | KDM4EGAATARBP2ALDH1A1LMNA | |
| SCHEMBL11619063 | 0.82 | KDM4E (0.65) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 | |
| SCHEMBL11620390 | 0.82 | MAPT (0.64) | KDM4EGAASMN1; SMN2TARBP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827097-B | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SAI NUOFEI (FR) | 2016-03-16 | — | — | CN | claimed |
| CN-105646362-B | 3- heteroaroylamino-propanoic derivatives and its purposes as drug | 赛诺菲 | 2019-07-05 | — | — | CN | disclosed |
| CN-103827097-B | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SAI NUOFEI (FR) | 2016-03-16 | — | — | CN | disclosed |