SCHEMBL28062312

SCHEMBL28062312

c1ccc(-c2ccccn2)cc1.c1ccc(-c2ccccn2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.68
LMNA P02545 4/20 0.68
CCR1 P32246 2/20 0.68
CCR5 P51681 2/20 0.68
CCR8 P51685 2/20 0.68
CYP1A2 P05177 2/20 0.68
POLB P06746 1/20 0.68
METAP1 P53582 1/20 0.68
BLM P54132 1/20 0.68
HIF1A Q16665 1/20 0.68
DOHH Q9BU89 1/20 0.68
P4HTM Q9NXG6 1/20 0.68
CYP2A6 P11509 1/20 0.64
RAB9A P51151 8/20 0.56
NPC1 O15118 7/20 0.56
TP53 P04637 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360780 1.00 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
Benzene SCHEMBL29224585 1.00 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL35754 1.00 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL6831244 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
SCHEMBL609602 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL9355925 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
SCHEMBL10628597 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16868474 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
Bromide SCHEMBL15901958 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7764586 0.97 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565594-B A kind of synthetic method without transition metal-catalyzed 2- phenylpyridine compound 大连理工大学 2019-06-25 CN disclosed
CN-102318102-B Electro-optical device and method for manufacturing the same NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2016-05-04 CN disclosed