SCHEMBL280626

SCHEMBL280626

FC(F)(F)C1=CCCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30933578 0.97
SCHEMBL6899661 0.84
SCHEMBL6414141 0.80
SCHEMBL22915910 0.80
SCHEMBL18295178 0.80
SCHEMBL21393844 0.78
SCHEMBL21083133 0.78
SCHEMBL3953181 0.78 CA1 (0.31)
SCHEMBL3416694 0.74
SCHEMBL9818195 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098450-A1 PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR 北京泰德制药股份有限公司 2025-05-15 WO disclosed
WO-2025048759-A1 BENZIMIDAZOLE DERIVATIVES AS MPGES-1 INHIBITORS ICOSYN THERAPEUTICS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) 2025-03-06 WO disclosed
WO-2024112287-A1 BENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF BANOGLU ERDEN (TR) 2024-05-30 WO disclosed
CN-117136189-A Ubiquitin-specific protease 1 (USP 1) inhibitors 先声再明医药有限公司 2023-11-28 CN disclosed
CN-116710425-A Pharmaceutical agents for the treatment of disorders involving lannodine receptors 阿姆果制药有限公司 2023-09-05 CN disclosed
CN-116462679-A Pyrazolopyrimidine derivative and application thereof in medicine 四川海思科制药有限公司 2023-07-21 CN disclosed
US-20230204838-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230204838-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
CN-113121521-B 6-trifluoromethyl-substituted benzothiazinone derivative, and preparation method and application thereof 苏州大学 2022-11-04 CN disclosed
CN-114269383-A Metalloenzyme inhibitor compounds 菲斯生物制药公司 2022-04-01 CN disclosed
WO-2011067272-A1 INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2011-06-09 WO disclosed
US-20110094321-A1 PREPARATION OF APREPITANT DR. REDDY'S LABORATORIES LIMITED (IN) 2011-04-28 US disclosed
EP-2181992-A1 POLYCYCLIC COMPOUND Eisai R&D Management Co., Ltd. (JP) 2010-05-05 EP disclosed
EP-1805141-B1 PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE MERCK SHARP & DOHME (GB) 2010-01-20 EP disclosed
EP-2103603-A1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND Japan Tobacco Inc. (JP) 2009-09-23 EP disclosed
WO-2008141077-A1 PROCESS FOR THE PREPARATION OF TETRAHYDROQUINOLINYL, BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-11-20 WO disclosed
WO-2008079427-A1 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-07-03 WO disclosed
WO-2007134149-A2 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2007-11-22 WO disclosed
EP-1292335-B1 COMBINATIONS AND COMPOSITIONS WHICH INTERFERE WITH VEGF/VEGF AND ANGIOPOIETIN/TIE RECEPTOR FUNCTION AND THEIR USE (II) BAYER SCHERING PHARMA AG (DE) 2007-05-30 EP disclosed
US-7199145-B2 Derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) 2007-04-03 US disclosed