SCHEMBL28063501

SCHEMBL28063501

CCc1cc2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3.[MgH2]

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.36
▸ STAT1 P42224 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ GRIN2D O15399 1/20 0.32
▸ GRIN3B O60391 1/20 0.32
▸ GRIN1 Q05586 1/20 0.32
▸ GRIN2A Q12879 1/20 0.32
▸ GRIN2B Q13224 1/20 0.32
▸ GRIN2C Q14957 1/20 0.32
▸ GRIN3A Q8TCU5 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31344426 0.98 STAT3 (0.37) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL144249 0.98 STAT3 (0.37) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL29790221 0.97 STAT3 (0.36) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL28106271 0.97 STAT3 (0.36) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL29470202 0.97 STAT3 (0.36) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL1944651 0.86 STAT3 (0.35) STAT3STAT1
SCHEMBL9097286 0.85 STAT3 (0.35) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL27911651 0.84 STAT3 (0.35) STAT3STAT1KDM4EMAPTALDH1A1
SCHEMBL3527778 0.83 STAT3 (0.34) STAT3STAT1
SCHEMBL28598440 0.83 KCNH2 (0.34) STAT3STAT1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106842617-A Optics 埃西勒国际通用光学公司 2017-06-13 — — CN disclosed
CN-104115054-B Ophthalmic filter 埃西勒国际通用光学公司 2017-03-01 — — CN disclosed
CN-103998974-B Optical device 埃西勒国际通用光学公司 2017-02-22 — — CN disclosed
CN-104024924-B The method determining the configuration of interference filter device and the method manufacturing optical mirror slip 埃西勒国际通用光学公司 2016-08-24 — — CN disclosed
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