SCHEMBL28064191

SCHEMBL28064191

Cc1cccc2ccccc12.Nc1cccc(N)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.71
ALDH1A1 P00352 5/20 0.71
CYP1A2 P05177 7/20 0.55
HSD17B10 Q99714 4/20 0.55
HPGD P15428 3/20 0.55
CYP3A4 P08684 3/20 0.50
CASP1 P29466 2/20 0.50
RECQL P46063 1/20 0.50
TSHR P16473 2/20 0.46
KEAP1 Q14145 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.42
SIGMAR1 Q99720 2/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
RAB9A P51151 1/20 0.41
CACNA1B Q00975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL28121040 0.89 CYP2A6 (0.74) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL11328666 0.85 CYP2A6 (0.81) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Methylamine SCHEMBL28280818 0.84 CYP2A6 (0.90) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL3075 0.84 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL10684163 0.84 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL29903166 0.84 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL7517852 0.84 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL7539708 0.82 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL14953945 0.82 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
O-Xylene SCHEMBL7050723 0.82 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105853246-A Keratin dyeing compositions comprising radical scavenger and chelant and use thereof 宝洁公司 2016-08-17 CN disclosed