Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.82 |
| ▸ | RAB9A | P51151 | 3/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Limantrafin SCHEMBL4638726 | 0.90 | KDM4E (1.00) | KDM4ERAB9APOLBMEN1KMT2A | |
| Limantrafin SCHEMBL25340427 | 0.90 | KDM4E (1.00) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL28055507 | 0.90 | KDM4E (0.82) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL30601045 | 0.90 | KDM4E (0.82) | KDM4ERAB9APOLBMEN1KMT2A | |
| Limantrafin SCHEMBL29221528 | 0.89 | KDM4E (0.97) | KDM4ERAB9APOLBMEN1KMT2A | |
| Limantrafin SCHEMBL30617842 | 0.89 | KDM4E (0.97) | KDM4ERAB9APOLBMEN1KMT2A | |
| Limantrafin SCHEMBL21597014 | 0.89 | KDM4E (0.97) | KDM4ERAB9APOLBMEN1KMT2A | |
| Limantrafin SCHEMBL30865022 | 0.89 | KDM4E (0.97) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL31225411 | 0.84 | KDM4E (0.73) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL15055437 | 0.84 | KDM4E (0.73) | KDM4ERAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541703-A | Triamine monomer containing pyridine structure and preparation method thereof | UNIV JILIN | 2016-05-04 | — | — | CN | disclosed |