Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494484 | 1.00 | HPGD (0.46) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL29053569 | 0.87 | HSD17B10 (0.61) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL24074547 | 0.87 | GRM2 (0.44) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27899621 | 0.86 | HSD17B10 (0.59) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL28064654 | 0.85 | IKBKB (0.39) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL30494403 | 0.84 | HSD17B10 (0.58) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL29053644 | 0.84 | HSD17B10 (0.58) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL28064557 | 0.83 | HDAC11 (0.47) | DHODHIKBKBCCNCCDK8MAPT | |
| SCHEMBL29053575 | 0.81 | HSD17B10 (0.58) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL30494411 | 0.81 | HSD17B10 (0.58) | HPGDHSD17B10MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555763-A | Indole-carboxamide derivatives | HOFFMANN LA ROCHE | 2016-05-04 | — | — | CN | claimed |
| CN-105555763-A | Indole-carboxamide derivatives | HOFFMANN LA ROCHE | 2016-05-04 | — | — | CN | disclosed |