Propene

Propene

SCHEMBL28064601

C=CC.CCOCc1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
CA1 P00915 4/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
IDO1 P14902 1/20 0.41
TP53 P04637 1/20 0.41
AGXT P21549 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TACR1 P25103 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL27782087 0.89 TSHR (0.64) TSHRCA1CA2CA7CA9
Propene SCHEMBL27428554 0.89 TSHR (0.71) TSHRCA1CA2CA7CA9
SCHEMBL16478 0.89 TSHR (0.70) TSHRCA1CA2CA7CA9
Vinyl Ether SCHEMBL27712853 0.88 TSHR (0.52) TSHRCA1CA2CA7CA9
SCHEMBL25430960 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9
SCHEMBL27473996 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9
Bromide SCHEMBL20577438 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9
Water SCHEMBL27893853 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9
Ammonia Solution, Strong SCHEMBL2308512 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9
SCHEMBL27338877 0.87 TSHR (0.67) TSHRCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503548-A Synthesizing method of fluorine halogenated vinyl ether JUHUA GROUP TECHNOLOGY CT 2016-04-20 CN disclosed