SCHEMBL28064695

SCHEMBL28064695

NCc1ccc(C[C@@H](N)CC(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.51
ENPEP Q07075 2/20 0.51
S1PR2 O95136 1/20 0.44
S1PR1 P21453 1/20 0.44
MMP2 P08253 2/20 0.44
EPHX1 P07099 1/20 0.43
CPA1 P15085 2/20 0.43
SLC7A5 Q01650 2/20 0.43
CPB1 P15086 1/20 0.43
CPA3 P15088 1/20 0.43
CPB2 Q96IY4 1/20 0.43
ERAP1 Q9NZ08 2/20 0.43
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC6A4 P31645 1/20 0.41
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ABAT P80404 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064620 1.00 ANPEP (0.51) ANPEPENPEPS1PR2S1PR1MMP2
SCHEMBL28064621 1.00 ANPEP (0.51) ANPEPENPEPS1PR2S1PR1MMP2
SCHEMBL28828020 0.86 ANPEP (0.49) ANPEPENPEPMMP2EPHX1CPA1
SCHEMBL28064623 0.86 ANPEP (0.49) ANPEPENPEPMMP2EPHX1CPA1
SCHEMBL28064622 0.86 ANPEP (0.49) ANPEPENPEPMMP2EPHX1CPA1
SCHEMBL25229867 0.85 SLC7A5 (0.61) ANPEPENPEPS1PR2S1PR1SLC7A5
SCHEMBL288929 0.85 ANPEP (0.51) ANPEPENPEPS1PR2S1PR1MMP2
SCHEMBL288276 0.85 SLC7A5 (0.61) ANPEPENPEPS1PR2S1PR1SLC7A5
SCHEMBL27999577 0.85 ANPEP (0.51) ANPEPENPEPS1PR2S1PR1MMP2
SCHEMBL197907 0.84 EPHX1 (0.64) ANPEPENPEPMMP2EPHX1CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555297-A WNT compositions and purification methods UNIV LELAND STANFORD JUNIOR 2016-05-04 CN disclosed