Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28828186 | 0.88 | MEN1 (0.42) | MEN1KMT2AHTTALDH1A1KDM4E | |
| Tert-Butyl Formate SCHEMBL28065015 | 0.86 | MEN1 (0.41) | MEN1KMT2AHTTALDH1A1KDM4E | |
| Tert-Butyl Formate SCHEMBL28209963 | 0.82 | PRCP (0.35) | MEN1KMT2AALDH1A1GAAHPGD | |
| Tert-Butyl Formate SCHEMBL28014694 | 0.74 | HTT (0.41) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL25076838 | 0.73 | MEN1 (0.48) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL30988665 | 0.71 | NR1H2 (0.43) | MEN1KMT2AHTTALDH1A1TP53 | |
| SCHEMBL31248547 | 0.71 | NR1H2 (0.43) | MEN1KMT2AHTTALDH1A1TP53 | |
| SCHEMBL31248558 | 0.71 | NR1H2 (0.43) | MEN1KMT2AHTTALDH1A1TP53 | |
| SCHEMBL5763372 | 0.71 | NR1H2 (0.43) | MEN1KMT2AHTTALDH1A1TP53 | |
| Tert-Butyl Formate SCHEMBL28824582 | 0.70 | HTT (0.38) | MEN1KMT2AHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |