Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439962 | 0.85 | ATM (0.65) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL31014408 | 0.82 | MKNK1 (0.50) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL28244717 | 0.82 | ATM (0.47) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL28065464 | 0.81 | MKNK2 (0.49) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL30240892 | 0.79 | HCAR2 (0.57) | MKNK1MKNK2TDP1KMT2ACYP2C9 | |
| SCHEMBL3209723 | 0.79 | CYP11B1 (0.58) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL186386 | 0.79 | HCAR2 (0.57) | MKNK1MKNK2TDP1KMT2ACYP2C9 | |
| SCHEMBL2201266 | 0.79 | CYP2C19 (0.66) | ATMMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL27775552 | 0.79 | KDM4E (0.50) | ATMKMT2A | |
| SCHEMBL9448469 | 0.78 | MKNK1 (0.66) | MKNK1MKNK2CYP11B1CYP11B2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593224-A | Novel quinazolinones as bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-05-18 | — | — | CN | disclosed |