Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856185 | 0.79 | TSHR (0.35) | GRIK1GRIK2KMT2A | |
| SCHEMBL1660557 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL1660555 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL1782070 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL22755767 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL28065532 | 0.74 | BACE1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL11336461 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL11336472 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL1782068 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL31019920 | 0.72 | GRIK1 (0.44) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103987700-B | 4-quinazoline amine derivant and application thereof | 江苏豪森药业集团有限公司 | 2016-08-31 | — | — | CN | disclosed |