SCHEMBL28066172

SCHEMBL28066172

O=CC1OCC(c2ccccc2)C(c2ccccc2)O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CYP2C19 P33261 6/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAOB P27338 8/20 0.34
MAOA P21397 7/20 0.34
KDM1A O60341 5/20 0.34
CYP2B6 P20813 3/20 0.34
CYP2C9 P11712 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
LMNA P02545 2/20 0.34
TAAR1 Q96RJ0 2/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CYP2A6 P11509 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28066085 0.79 TSHR (0.36) TSHRCHRM2CHRM4CHRM5CHRM1
SCHEMBL27716177 0.79 TSHR (0.52) TSHRMAOBHTR1AADRA2ASLC6A2
SCHEMBL28181121 0.77 EPHX1 (0.41) TSHRCYP2C19MAOBMAOAKDM1A
SCHEMBL28148902 0.74 TSHR (0.45) TSHRCYP2C19MEN1KMT2AMAPT
SCHEMBL27384719 0.70 TSHR (0.50) TSHRCYP2C19MEN1KMT2AMAOB
SCHEMBL27696288 0.69 EPHX1 (0.35) TSHRCYP2C19MEN1KMT2ACYP2D6
SCHEMBL28576105 0.69 TSHR (0.44) TSHRMAOBSLC6A2SLC6A3HSD17B10
SCHEMBL28066086 0.69 TSHR (0.44) TSHRMAOBSLC6A2SLC6A3HSD17B10
SCHEMBL28574468 0.69 TSHR (0.44) TSHRMAOBSLC6A2SLC6A3HSD17B10
SCHEMBL27968071 0.68 TSHR (0.38) TSHRMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105580189-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2016-05-11 CN disclosed