Oxirane

Oxirane

SCHEMBL28066237

C1CO1.C=CCOc1cccc2ccccc12

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2A6 P11509 1/20 0.49
HTR1B P28222 5/20 0.47
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
SETDB1 Q15047 1/20 0.46
ATM Q13315 1/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA9 Q16790 2/20 0.46
KCNA3 P22001 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR1D P28221 1/20 0.44
CASP1 P29466 1/20 0.44
SLC6A4 P31645 1/20 0.43
HRH1 P35367 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4371294 0.92 HPGD (0.56) HPGDCYP3A4CYP2A6HTR1BKDM4E
Ethylene SCHEMBL3362752 0.90 HPGD (0.55) HPGDCYP3A4CYP2A6HTR1BKDM4E
Water SCHEMBL21694712 0.90 HPGD (0.55) HPGDCYP3A4CYP2A6HTR1BKDM4E
Ether SCHEMBL21694709 0.83 HPGD (0.49) HPGDCYP3A4CYP2A6HTR1BKDM4E
SCHEMBL3820470 0.80 CYP3A4 (0.57) HPGDCYP3A4CYP2A6KDM4EALDH1A1
SCHEMBL27421928 0.77 HTR1B (0.56) HPGDHTR1BKDM4EALDH1A1ATM
SCHEMBL1394420 0.77 HTR1B (0.58) HPGDHTR1BKDM4EALDH1A1CYP1A2
SCHEMBL3820950 0.77 HPGD (0.54) HPGDCYP3A4CYP2A6KDM4EALDH1A1
SCHEMBL28113815 0.75 HTR1B (0.49) HPGDHTR1BKDM4EALDH1A1CYP1A2
Oxirane SCHEMBL11776735 0.75 HTR1B (0.46) HPGDHTR1BKDM4EALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105246831-B Magnesium oxide particle production method 堺化学工业株式会社 2017-05-03 CN disclosed
CN-103275800-B Lubricant oil composite 吉坤日矿日石能源株式会社 2016-06-22 CN disclosed
CN-105246831-A Magnesium oxide particles, magnesium oxide particle production method, resin composition and molded body using such resin composition, and adhesive or grease SAKAI CHEMICAL INDUSTRY CO 2016-01-13 CN disclosed
CN-103003402-B Lubricating oil composition for low-friction sliding material and sliding mechanism using same IDEMITSU KOSAN CO.,LTD. (JP) 2015-09-09 CN disclosed
CN-101629124-A Four stroke engine oil base oil and usage NIPPON OIL CORP 2010-01-20 CN disclosed
CN-100567467-C four-stroke engine oil base oil and composition NIPPON OIL CORP (JP) 2009-12-09 CN disclosed
CN-100362217-C Tappet for internal combustion engine NISSAN MOTOR (JP) 2008-01-16 CN disclosed
CN-1325822-C Piston for internal combustion engine NISSAN MOTOR (JP) 2007-07-11 CN disclosed
CN-1580503-A Tappet for internal combustion engine NISSAN MOTOR (JP) 2005-02-16 CN disclosed
CN-1573143-A Rolling element NISSAN MOTOR (JP) 2005-02-02 CN disclosed
CN-1573177-A Piston for internal combustion engine NISSAN MOTOR (JP) 2005-02-02 CN disclosed
CN-1524933-A four-stroke engine oil base oil and composition 新日本石油株式会社 2004-09-01 CN disclosed