Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.53 |
| ▸ | ACE | P12821 | 4/20 | 0.53 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | TPH1 | P17752 | 8/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077591 | 0.96 | MME (0.49) | MMEACECPA1ACE2ALPI | |
| SCHEMBL13957286 | 0.90 | MME (0.62) | MMEACECPA1ACE2HTR2A | |
| SCHEMBL16252292 | 0.90 | MME (0.62) | MMEACECPA1ACE2HTR2A | |
| Phenylalanine SCHEMBL27785427 | 0.86 | SLC7A5 (0.71) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL24766201 | 0.83 | MME (0.65) | MMEACECPA1ACE2CA2 | |
| Alanine SCHEMBL28096571 | 0.83 | HTR2A (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL93304 | 0.83 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL29584308 | 0.83 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL837890 | 0.83 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL93303 | 0.83 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103601792-B | It is effective to the guanylate cyclase agonist of gastrointestinal dysfunction, inflammation, cancer and other diseases treatment | 协同医药品公司 | 2016-06-29 | — | — | CN | disclosed |