SCHEMBL28066876

SCHEMBL28066876

OP(O)OCc1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.52
AGER Q15109 1/20 0.42
APP P05067 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
MAOB P27338 3/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
SMPD1 P17405 1/20 0.39
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5439593 0.86 IDO1 (0.52) IDO1AGERAPPRXRARXRB
SCHEMBL8389173 0.81 IDO1 (0.52) IDO1APPKDM4EKMT2AALOX15
SCHEMBL9715924 0.77 IDO1 (0.52) IDO1APPMAOBKMT2AMAPT
SCHEMBL2128784 0.76 TSHR (0.52) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL11445554 0.76 AGXT (0.50) IDO1MAOBKDM4EKMT2AALOX15
SCHEMBL11444701 0.74 TSHR (0.50) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL11444625 0.74 TSHR (0.50) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL8389197 0.74 IDO1 (0.55) IDO1APPMAOB
Ethylene SCHEMBL11652287 0.73 TSHR (0.48) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL5953661 0.72 IDO1 (0.47) IDO1APPRXRARXRBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105712917-B Conjugated type sulfosalt light trigger, preparation method and applications with light trigger and photosensitizer dual-use function 同济大学 2017-12-26 CN claimed
CN-104238268-B Sulfosalt class photo-acid agent based on triphenylethylene, preparation method and applications 同济大学 2017-12-26 CN claimed
CN-105712917-A Conjugated type sulfonium salt photoinitiator with double functions of photoinitiator and photosensitizer, preparation method and application of conjugated type sulfonium salt photoinitiator 同济大学 2016-06-29 CN claimed
CN-110105166-A Alpha-hydroxy ketones and its preparation method and application containing talan 同济大学 2019-08-09 CN disclosed
CN-106905169-B A kind of vinyl conjugation tri-arylamine group charge transport materials and preparation method thereof 中山大学 2019-02-22 CN disclosed
CN-104238268-B Sulfosalt class photo-acid agent based on triphenylethylene, preparation method and applications 同济大学 2017-12-26 CN disclosed
CN-106905169-A A kind of vinyl conjugation tri-arylamine group charge transport materials and preparation method thereof 中山大学 2017-06-30 CN disclosed
CN-105712917-A Conjugated type sulfonium salt photoinitiator with double functions of photoinitiator and photosensitizer, preparation method and application of conjugated type sulfonium salt photoinitiator 同济大学 2016-06-29 CN disclosed