SCHEMBL28067063

SCHEMBL28067063

O=CC=C=CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH7 P40394 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ARG2 P78540 1/20 0.35
F2 P00734 1/20 0.34
PLG P00747 1/20 0.34
ELANE P08246 1/20 0.34
CTSG P08311 1/20 0.34
CMA1 P23946 1/20 0.34
CTRC Q99895 1/20 0.34
EPHX1 P07099 1/20 0.34
TOP1 P11387 1/20 0.33
CALM1 P0DP23 1/20 0.33
CCNB2 O95067 1/20 0.33
CDK1 P06493 1/20 0.33
CDK4 P11802 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20211960 0.79 MAOB (0.44) MAOBCA1CA2ARG2CALM1
SCHEMBL7124438 0.75 MAOB (0.46) MAOBCMA1CCNB2CDK1CDK4
SCHEMBL7070788 0.75 MAOB (0.46) MAOBCMA1CCNB2CDK1CDK4
SCHEMBL29054488 0.74 MAOB (0.48) MAOBCA1CA2ARG2CALM1
SCHEMBL57808 0.73 MAOB (0.52) MAOBADH1BADH1CADH1AADH7
SCHEMBL19178921 0.72 MAOB (0.46) MAOBCA1CA2ARG2CALM1
Phenylacetaldehyde SCHEMBL3319438 0.71 MAOB (0.63) MAOBADH1BADH1CADH1AADH7
Phenylacetaldehyde SCHEMBL18972 0.71
Phenylacetaldehyde SCHEMBL31402006 0.71
Phenylacetaldehyde SCHEMBL31725265 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105541581-A Stereospecific synthesized tetra-substituted olefin compound and novel method therefor UNIV ZHEJIANG 2016-05-04 CN disclosed