Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488832 | 0.87 | HPRT1 (0.50) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL18904437 | 0.87 | KDM4E (0.46) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL24608533 | 0.87 | KDM4E (0.64) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL24608535 | 0.85 | CCR1 (0.49) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL27012142 | 0.85 | KDM4E (0.50) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL13408678 | 0.84 | KDM4E (0.50) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL19275986 | 0.84 | CCR1 (0.51) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL12210850 | 0.84 | DHODH (0.45) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL15835310 | 0.83 | CCR1 (0.56) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL12210961 | 0.82 | HSD17B10 (0.47) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104692986-B | Synthetic method of medical intermediate phenanthrene compound | TAN YONGSHAN (CN) | 2016-05-25 | — | — | CN | disclosed |