Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16733061 | 0.97 | — | — | |
| SCHEMBL6566051 | 0.97 | — | — | |
| SCHEMBL970446 | 0.97 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5554344 | 0.97 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27780072 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9244902 | 0.90 | — | — | |
| Bromide SCHEMBL3654783 | 0.87 | — | — | |
| SCHEMBL970599 | 0.83 | — | — | |
| Iodide SCHEMBL29108768 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL16732626 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106165105-B | Organic transistor, semiconductor film, method for producing organic transistor, method for producing semiconductor film, coating liquid for non-light-emitting organic semiconductor device, material, and compound | 富士胶片株式会社 | 2019-07-09 | — | — | CN | disclosed |
| CN-106165105-A | Coating liquid for non-light-emitting organic semiconductor device, organic transistor, compound, organic semiconductor material for non-light-emitting organic semiconductor device, material for organic transistor, method for producing organic transistor, and method for producing organic semiconductor film | 富士胶片株式会社 | 2016-11-23 | — | — | CN | disclosed |
| CN-105601662-A | Compound used for forming high-molecular compound | SUMITOMO CHEMICAL CO | 2016-05-25 | — | — | CN | disclosed |