Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16149870 | 0.95 | HPGD (0.66) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL971083 | 0.84 | HPGD (1.00) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL644199 | 0.84 | HPGD (0.92) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL578679 | 0.83 | POLB (0.87) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL12621027 | 0.83 | POLB (0.87) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL2646094 | 0.83 | HPGD (0.70) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL28219187 | 0.83 | HPGD (0.70) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL24185725 | 0.82 | HPGD (0.96) | HPGDCA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL21590292 | 0.82 | HPGD (0.89) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL969583 | 0.82 | HPGD (0.96) | HPGDCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492008-A | Novel compounds and compositions for inhibition of fasn | FORMA THERAPEUTICS INC | 2016-04-13 | — | — | CN | disclosed |
| CN-101155799-A | Pyrimidine inhibitors of kinases | TARGEGEN INC (US) | 2008-04-02 | — | — | CN | disclosed |