Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL319125 | 1.00 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL252928 | 1.00 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28124478 | 1.00 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28496066 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28813030 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28193527 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL29173182 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL29085649 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27993249 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28147762 | 0.97 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108300591-A | A kind of detergent composition and preparation method thereof with antibacterial functions | 纳爱斯浙江科技有限公司 | 2018-07-20 | — | — | CN | claimed |
| CN-110382205-A | Core-shell filament for printing smooth FDM 3D articles | 昕诺飞控股有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110337292-A | Pharmaceuticals | 兴和株式会社 | 2019-10-15 | — | — | CN | disclosed |
| CN-109982850-A | Powder coated FDM printed article, related manufacturing method and apparatus | 昕诺飞控股有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109874325-A | The method for obtaining specular reflection surface using FDM | 昕诺飞控股有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-109705318-A | A kind of method and Polyester color master batch of continuous production of polyesters Masterbatch | 中国纺织科学研究院有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109705320-A | A kind of method and polyester functional agglomerate of continuous production of polyesters functional agglomerate | 中国纺织科学研究院有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108300591-A | A kind of detergent composition and preparation method thereof with antibacterial functions | 纳爱斯浙江科技有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-104159970-B | Polyester resin composition, process for producing the same, and molded article using the same | MITSUBISHI GAS CHEMICAL CO.,INC. (JP) | 2016-05-25 | — | — | CN | disclosed |