Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634613 | 0.91 | IDO1 (0.39) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634612 | 0.91 | IDO1 (0.39) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634784 | 0.88 | HDAC3 (0.38) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634783 | 0.88 | HDAC3 (0.38) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634994 | 0.81 | IDO1 (0.41) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634993 | 0.81 | IDO1 (0.41) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634749 | 0.77 | IDO1 (0.40) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634748 | 0.77 | IDO1 (0.40) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634704 | 0.76 | IDO1 (0.37) | IDO1GAACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16634705 | 0.76 | IDO1 (0.37) | IDO1GAACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636938-A | Method for preparation of 3-alkylthio-2-bromopyridine | LG LIFE SCIENCES LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105636938-A | Method for preparation of 3-alkylthio-2-bromopyridine | LG LIFE SCIENCES LTD | 2016-06-01 | — | — | CN | disclosed |