Cyclohexane

Cyclohexane

SCHEMBL28068226

C1CCCCC1.Cc1cccs1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.38
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
FBP1 P09467 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PRCP P42785 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
RAB9A P51151 3/20 0.34
NPC1 O15118 2/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17873 0.91
SCHEMBL9413954 0.91
SCHEMBL3976184 0.88
Lithium SCHEMBL31489997 0.88
Benzene SCHEMBL1522440 0.88 DAO (0.40) FBP1RAB9ANPC1ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL354013 0.88
Ethane SCHEMBL23798741 0.88
Hydrogen Sulfide SCHEMBL16932225 0.88
Iodide SCHEMBL11106814 0.88
Hydrochloric Acid SCHEMBL2951155 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636965-B The ring type compound of sulfur-bearing two 安斯泰来制药株式会社 2017-11-24 CN disclosed
CN-105636965-A Sulfur-containing bicyclic compound ASTELLAS PHARMA INC 2016-06-01 CN disclosed