Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.61 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ESYT2 | A0FGR8 | 1/20 | 0.58 |
| ▸ | PLEKHG3 | A1L390 | 1/20 | 0.58 |
| ▸ | NBAS | A2RRP1 | 1/20 | 0.58 |
| ▸ | CNOT1 | A5YKK6 | 1/20 | 0.58 |
| ▸ | TBKBP1 | A7MCY6 | 1/20 | 0.58 |
| ▸ | MYO1G | B0I1T2 | 1/20 | 0.58 |
| ▸ | AGPS | O00116 | 1/20 | 0.58 |
| ▸ | MYO1F | O00160 | 1/20 | 0.58 |
| ▸ | SNAP23 | O00161 | 1/20 | 0.58 |
| ▸ | AP3B1 | O00203 | 1/20 | 0.58 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.58 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.58 |
| ▸ | PGRMC1 | O00264 | 1/20 | 0.58 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119546 | 0.79 | BRAF (0.82) | PIK3CABCDIN3DLMNAHSP90AA1MAPK1 | |
| SCHEMBL22025030 | 0.78 | BRAF (0.81) | PIK3CALMNAHSP90AA1MAPK1HSD17B10 | |
| SCHEMBL22024695 | 0.77 | BRAF (0.86) | LMNAHSP90AA1MAPK1HSD17B10ESYT2 | |
| SCHEMBL22025026 | 0.77 | BRAF (0.82) | LMNAHSP90AA1MAPK1HSD17B10ESYT2 | |
| SCHEMBL22024561 | 0.76 | BRAF (0.81) | LMNAHSP90AA1MAPK1HSD17B10ESYT2 | |
| SCHEMBL29582202 | 0.75 | BCDIN3D (1.00) | BCDIN3DCDK1PRKCA | |
| SCHEMBL22806070 | 0.75 | BCDIN3D (1.00) | BCDIN3DCDK1PRKCA | |
| SCHEMBL13943721 | 0.75 | MEN1 (0.68) | PIK3CABCDIN3DLMNAHSP90AA1MAPK1 | |
| SCHEMBL22025313 | 0.75 | BRAF (0.80) | LMNAHSP90AA1MAPK1HSD17B10ESYT2 | |
| SCHEMBL22024565 | 0.75 | KDR (0.53) | PIK3CABCDIN3DLMNAHSP90AA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |