⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552440 | 0.84 | KDM4E (0.37) | — | |
| SCHEMBL8769452 | 0.72 | — | — | |
| SCHEMBL2120614 | 0.71 | — | — | |
| SCHEMBL14952766 | 0.69 | — | — | |
| SCHEMBL29138444 | 0.67 | — | — | |
| SCHEMBL5178799 | 0.67 | — | — | |
| SCHEMBL25437536 | 0.67 | — | — | |
| SCHEMBL2122507 | 0.67 | — | — | |
| SCHEMBL111375 | 0.67 | — | — | |
| SCHEMBL8769936 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764341-A | Use of substituted dihydrooxindole sulfonamides or salts thereof for increasing stress tolerance in plants | 拜耳作物科学股份公司 | 2016-07-13 | — | — | CN | claimed |
| CN-106316975-A | Amide compound and application thereof as TGR5 agonist | 山东轩竹医药科技有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104011026-B | Insecticidal aromatic amides | 拜耳知识产权股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105764341-A | Use of substituted dihydrooxindole sulfonamides or salts thereof for increasing stress tolerance in plants | 拜耳作物科学股份公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-103965119-B | Irreversible EGFR tyrosine kinase inhibitor containing zinc binding moiety | 通化济达医药有限公司 | 2016-07-06 | — | — | CN | disclosed |