Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248401 | 0.72 | POLB (0.48) | POLBAPEX1CYP2C19MMP2MMP7 | |
| SCHEMBL9978332 | 0.72 | — | — | |
| SCHEMBL1159961 | 0.67 | — | — | |
| SCHEMBL17323652 | 0.67 | POLB (0.42) | POLBCYP2C19 | |
| SCHEMBL830748 | 0.65 | POLB (1.00) | POLBAPEX1CYP2C19MMP2MMP7 | |
| SCHEMBL7478797 | 0.65 | POLB (0.40) | POLBCYP2C19 | |
| SCHEMBL71944 | 0.63 | — | — | |
| SCHEMBL7962385 | 0.63 | POLB (0.93) | POLBAPEX1CYP2C19MMP2MMP7 | |
| SCHEMBL28931522 | 0.61 | POLB (0.56) | POLBAPEX1CYP2C19MMP2MMP7 | |
| SCHEMBL11502274 | 0.61 | POLB (0.48) | POLBAPEX1CYP2C19MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636592-A | Pro-drug forming compounds | EVESTRA INC | 2016-06-01 | — | — | CN | disclosed |