Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829382 | 1.00 | CYP3A4 (0.38) | CYP3A4TDP1DRD1TSHRMAOA | |
| SCHEMBL28910351 | 0.81 | EPHX1 (0.44) | CYP3A4TDP1MAOASLC6A4TAAR1 | |
| SCHEMBL10001653 | 0.80 | TSHR (0.50) | CYP3A4TDP1DRD1TSHRESR1 | |
| SCHEMBL668759 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1DRD1MAOAESR1 | |
| SCHEMBL29053288 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1DRD1MAOAESR1 | |
| SCHEMBL16292891 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1DRD1MAOAESR1 | |
| SCHEMBL2846076 | 0.79 | CYP3A4 (0.46) | CYP3A4TDP1DRD1TSHRESR1 | |
| SCHEMBL3678678 | 0.76 | TSHR (0.44) | TSHRMAOASLC6A4TAAR1SLC6A2 | |
| SCHEMBL2850051 | 0.76 | CYP3A4 (0.42) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL23581097 | 0.75 | CYP3A4 (0.46) | CYP3A4TDP1DRD1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732726-B | A kind of preparation method and use of camphorated imines Phosphine ligands | 杭州师范大学 | 2018-06-29 | — | — | CN | disclosed |
| CN-105777806-B | A kind of camphorated imines Phosphine ligands | 杭州师范大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-105777806-A | Imine ligand containing camphor | 杭州师范大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105732726-A | Synthesis method and application of imine phosphine ligand containing camphor | 杭州师范大学 | 2016-07-06 | — | — | CN | disclosed |