Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439512 | 0.89 | PTPN1 (0.44) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL27722046 | 0.85 | MEN1 (0.44) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL27819507 | 0.84 | PTPN1 (0.44) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL28089352 | 0.81 | PTPN1 (0.48) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL4998879 | 0.79 | MAPT (0.44) | PTPN1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5702932 | 0.77 | MEN1 (0.54) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL9333813 | 0.77 | PTPN1 (0.64) | PTPN1HSD17B10ALDH1A1KDM4ETPMT | |
| SCHEMBL27572490 | 0.77 | PTPN1 (0.44) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL9134557 | 0.77 | MEN1 (0.40) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL27730255 | 0.77 | PTPN1 (0.44) | PTPN1HSD17B10ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801482-A | Method for preparing 1-cyclopropyl-4-oxo-7-bromine-8-difluoromethoxy-1,4-dihydro-quinoline-3-nonanoic acid-ethyl ester | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105777631-A | Synthesizing method of 1-cyclopropyl-4-oxo-7-bromo-8-difluoromethoxy-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester | 浙江中欣氟材股份有限公司 | 2016-07-20 | — | — | CN | disclosed |