Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507242 | 1.00 | DPP4 (0.68) | DPP4OPRM1OPRK1CYP1A2CYP3A4 | |
| SCHEMBL13185937 | 0.90 | DPP4 (0.66) | DPP4OPRM1OPRK1 | |
| SCHEMBL17781891 | 0.90 | DPP4 (0.66) | DPP4OPRM1OPRK1 | |
| SCHEMBL16280698 | 0.85 | DPP4 (0.72) | DPP4CYP1A2CYP3A4CYP2D6RET | |
| SCHEMBL28324302 | 0.83 | DPP4 (0.69) | DPP4RET | |
| SCHEMBL2022448 | 0.82 | DPP4 (0.69) | DPP4RET | |
| SCHEMBL2022446 | 0.82 | DPP4 (0.69) | DPP4RET | |
| SCHEMBL10331078 | 0.82 | DPP4 (0.84) | DPP4OPRM1OPRK1CYP1A2CYP3A4 | |
| SCHEMBL13141899 | 0.82 | DPP4 (0.84) | DPP4OPRM1OPRK1CYP1A2CYP3A4 | |
| SCHEMBL18851350 | 0.81 | DPP4 (0.67) | DPP4RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646447-A | Synthesis method of dipeptidyl peptidase inhibitor | 北京康立生医药技术开发有限公司 | 2016-06-08 | — | — | CN | disclosed |