Ethane

Ethane

SCHEMBL28069740

CC.Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.89
MAPK1 P28482 2/20 0.89
TSHR P16473 6/20 0.52
HSD17B10 Q99714 6/20 0.48
HPGD P15428 3/20 0.48
HSP90AA1 P07900 2/20 0.48
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
AR P10275 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
AHR P35869 2/20 0.36
KDM4E B2RXH2 1/20 0.34
BRD4 O60885 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
METAP2 P50579 1/20 0.34
METAP1 P53582 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28055212 0.94 CYP3A4 (0.89) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL136940 0.94 CYP3A4 (1.00) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL27287703 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL27286341 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL27375138 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
Hydrochloric Acid SCHEMBL11673852 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
Methane SCHEMBL28776381 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL11876110 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL2812523 0.92 CYP3A4 (0.94) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL11119604 0.89 CYP3A4 (0.89) CYP3A4MAPK1TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566309-A Method for synthesizing Luliconazole HUNAN TRADITIONAL CHINESE MEDICAL COLLEGE 2016-05-11 CN disclosed